Toxoplasma Retromer Is Here to Stay

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• 作者：Olivia L. McGovern¹ ; Vern B. Carruthers¹ ; ^{vcarruth@umich.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：parasite ; membrane ; protein ; trafficking ; targeting
• 刊名：Trends in Parasitology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：32
• 期：10
• 页码：758-760
• 全文大小：535 K

文摘

How the protozoan pathogen Toxoplasma gondii and related parasites shuttle proteins through their intricate system of endomembranous compartments remains unclear. Sangaré et al. show that the Toxoplasma retromer complex is essential for parasite viability through its role in protein targeting to multiple locales and its interactions with newly identified partners.