Expression patterns of ERVWE1/Syncytin-1 and other placentally expressed human endogenous retroviruses along the malignant transformation process of hydatidiform moles
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- 作者：Pierre-Adrien Bolzea ; b ; c ; pierre-adrien.bolze@chu-lyon.fr" class="auth_mail" title="E-mail the corresponding author ; Sophie Patrierb ; d ; sophie.patrier@chu-rouen.fr" class="auth_mail" title="E-mail the corresponding author ; Valé ; rie Cheynetc ; valerie.cheynet@biomerieux.com" class="auth_mail" title="E-mail the corresponding author ; Guy Oriolc ; guy.oriol@biomerieux.com" class="auth_mail" title="E-mail the corresponding author ; Jé ; rô ; me Massardiere ; jerome.massardier@chu-lyon.fr" class="auth_mail" title="E-mail the corresponding author ; Touria Hajrib ; touria.hajri@chu-lyon.fr" class="auth_mail" title="E-mail the corresponding author ; Michè ; le Guillottef ; michele.guillotte@biomerieux.com" class="auth_mail" title="E-mail the corresponding author ; Marc Bossusf ; marc.bossus@biomerieux.com" class="auth_mail" title="E-mail the corresponding author ; Damien Sanlavilleg ; damien.sanlaville@chu-lyon.fr" class="auth_mail" title="E-mail the corresponding author ; Franç ; ois Golfiera ; b ; francois.golfier@chu-lyon.fr" class="auth_mail" title="E-mail the corresponding author ; Franç ; ois Malletc ; h ; francois.mallet@biomerieux.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Choriocarcinoma ; Human endogenous retroviruses ; Gestational trophoblastic disease ; Gestational trophoblastic neoplasia ; Hydatidiform mole ; Syncytin-1
- 刊名：Placenta
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：116-124
- 全文大小：2848 K
文摘
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Syncytin-1 glycoprotein is expressed in the syncytiotrophoblast of hydatidiform moles.
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Syncytin-1 interaction partners TLR4 and hASCT1 are down regulated in complete moles.
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Syncytin-1 surface-unit is overexpressed in moles with further malignant transformation.