Group 2 innate lymphoid cells are increased in nasal polyps in patients with eosinophilic chronic rhinosinusitis
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- 作者：Ichiro Tojimaa ; itirotz@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Hideaki Kouzakia ; Shino Shimizua ; Takao Ogawaa ; Masahiko Arikataa ; Hirohito Kitab ; Takeshi Shimizua
- 关键词：ILC2s ; group 2 innate lymphoid cells ; CRS ; chronic rhinosinusitis ; CRSwNP ; chronic rhinosinusitis with nasal polyps ; CRSsNP ; chronic rhinosinusitis without nasal polyps ; ECRS ; eosinophilic chronic rhinosinusitis ; UTs ; uncinate tissues ; NPs ; nasal polyps ; AR ; allergic rhinitis ; FACS ; fluorescence-activated cell sorting ; PBMCs ; peripheral blood mononuclear cells
- 刊名：Clinical Immunology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：170
- 期：Complete
- 页码：1-8
- 全文大小：869 K
文摘
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The prevalence of ILC2s in nasal polyps was high in patients with ECRS.
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The prevalence of ILC2s in blood was not different between ECRS and non-ECRS.
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The prevalence of ILC2s in blood was high in patients with allergic rhinitis.
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The prevalence of ILC2s in blood was low in patients with asthma.
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Alternaria-induced IL-33 secretion was increased in nasal epithelial cells of ECRS.