FRET-based nanobiosensor for detection of scopolamine in hairy root extraction of Atropa belladonna

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• 作者：Fereshte Bagheri^a ; ^b ; ^{f.bagheri2016@yahoo.com} ; Khosro Piri^a ; ^{khpiri@gmail.com} ; Afshine Mohsenifar^c ; ^{mohsenifar_a@yahoo.com} ; Smaiil Ghaderi^d
• 关键词：Nanobiosensor ; FRET ; Cd/Te quantum dots ; M2 muscarinic receptor ; Tropane alkaloids ; Hairy roots
• 刊名：Talanta
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：164
• 期：Complete
• 页码：593-600
• 全文大小：750 K
• 卷排序：164

文摘

A novel, sensitive, selective and rapid optical nanobiosensor method is developed. This method based on FRET, nanobio conjugation of CdTe-TGA-M2 muscarinic receptor and conjugation of scopolamine- rhodamine123 as donor/acceptor pair, respectively. This system, responses for scopolamine hydrochloride (Tropane alkaloids) determination in extract of hairy roots of Atropa belladonna. Nanobiosensor be able easily for in-vitro determination of anticholinergic agent in plant extracts.