Silencing the odorant receptor co-receptor RproOrco affects the physiology and behavior of the Chagas disease vector Rhodnius prolixus
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- 作者：Thiago A. Francoa ; 1 ; Daniele S. Oliveiraa ; 1 ; Monica F. Moreiraa ; c ; Walter S. Lealb ; Ana C.A. Meloa ; b ; c ; anamelo@iq.ufrj.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rhodnius prolixus ; Odorant co-receptor ; Orco ; Interfering RNA
- 刊名：Insect Biochemistry and Molecular Biology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：69
- 期：Complete
- 页码：82-90
- 全文大小：1817 K
文摘
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RproOrco is highly expressed in the antennae of all stages of R. prolixus.
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The RNAi technique effectively silenced the gene in both males and females.
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Insects with silenced RproOrco are unable to find a vertebrate host in a timely manner.
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Orco silencing affects the insects' capacity to engorge on blood, decreases ecdysis and oviposition rates and increases the mortality rate.
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The RNAi is a powerful tool that could be applied in the control strategy for blood-sucking, disease-carrying insects.