Mammary analog secretory carcinoma of the parotid gland: A case report and literature review.
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- 作者：Ricardo Balanzá ; a ; balanza.ricardo@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Rodrigo Arrangoizb ; rodrigo.arrangoiz@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Fernando Corderab ; Manuel Muñ ; ozb ; Enrique Luque-de-Leó ; nb ; Eduardo Morenob ; Carlos Toledob ; Edgar Gonzá ; lezb
- 刊名：International Journal of Surgery Case Reports
- 出版年：2015
- 出版时间：2015
- 年：2015
- 卷：16
- 期：Complete
- 页码：187-191
- 全文大小：2074 K
文摘
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Mammary analog secretory carcinoma (MASC) is a newly described carcinoma of the salivary glands.
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MASC is characterized by morphologic and immunohistochemical features that strongly resemble a secretory carcinoma (SC) of the breast.
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MASC and SC of the breast share the presence of translocation t(12;15) (p13;q25), that results in the formation of an oncogenic fusion gene ETV6-NTK3.
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The majority of MASC present among men and arise from the parotid gland.
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MASC is a low-grade carcinoma with potential for high-grade transformation.