Expression of several cytokines in prostate cancer: Correlation with clinical variables of patients. Relationship with biochemical progression of the malignance

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• 作者：Norelia Torrealba^a ; ¹ ; ^{engastediamante@gmail.com} ; Gonzalo Rodr&iacute ; guez-Berriguete^a ; ¹ ; ^{gonzalo_rb@hotmail.es} ; Benito Fraile^a ; ^{benito.fraile@uah.es} ; Gabriel Olmedilla^b ; ^{golmedilla.hupa@salud.madrid.org} ; Pilar Mart&iacute ; nez-Onsurbe^b ; ^{mmonsurbe@salud.madrid.org} ; Manuel Guil-Cid^c ; ^{manuelesteban.guil@salud.madrid.org} ; Ricardo Paniagua^a ; ^{Ricardo.paniagua@uah.es} ; Mar Royuela^a ; ^{mar.royuela@uah.es}
• 关键词：IL-1 ; IL-6 ; EGF ; TNF-alfa ; TGF-B and prostate cancer
• 刊名：Cytokine
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：89
• 期：Complete
• 页码：105-115
• 全文大小：1363 K
• 卷排序：89

文摘

In PC TNF-α, EGF, IL-1α, IL-1RII and IL-1Ra were observed in epithelial cells. Increased EGFR and reduced IL-1α/TGF-B correlated with biochem. progression. IL-1α and intensity TGFBRI predicted biochemical progression. Expression of TGF-B, IL-1α, TGFBRI and TGFBRII as prognostic markers for PC.