Infarct extent by MRI corelates with peak serum troponin level in the canine model¹

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• 作者：Gallegos ; Robert P. ; Swingen ; Cory ; Xu ; Xunhai James ; Wang ; Xiaoen ; Bianco ; Richard ; Jerosch-Herold ; Michael ; et. al.
• 关键词：Troponin I ; MRI ; myocardial infarction ; biological markers ; blood immunoassay
• 刊名：Journal of Surgical Research
• 出版年：2004
• 出版时间：August, 2004
• 年：2004
• 卷：120
• 期：2
• 页码：266-271
• 全文大小：340 K

文摘

Serum Troponin I is used routinely as an adjunct to EKG for the diagnosis of myocardial infarction (MI); however, a correlation between marker level and infarct size has yet to be documented in vivo. We report findings from a chronic coronary artery ligation model in the canine (n = 12) in which peak Troponin I is related to infarct size as determined by high-resolution cardiac magnetic resonance imaging.