Semantic cognition depends on connectivity of semantic hub with input/output systems.
We examined the connectivity of the left ATL and PL sub-regions during speech.
An ATL sub-region was linked to Broca's area and sensory-motor cortices during Speech.
A PL subregion was linked to systems involved in predominantly perceptual processing of picture stimuli.
The left ATL connects the proposed semantic hub to output systems for overt speech production.