Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4+ T Cell Immunity
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- 作者：Deshapriya S. Karunarathne1 ; 10 ; Joshua M. Horne-Debets1 ; 10 ; Johnny X. Huang2 ; Rebecca Faleiro1 ; Chiuan Yee Leow1 ; Fiona Amante1 ; Thomas S. Watkins1 ; John J. Miles1 ; Patrick J. Dwyer3 ; Katryn J. Stacey4 ; Michael Yarski5 ; Chek Meng Poh6 ; 7 ; Jason S. Lee1 ; Matthew A. Cooper2 ; Laurent Ré ; nia6 ; 7 ; Derek Richard8 ; James S. McCarthy1 ; Arlene H. Sharpe9 ; Michelle N. Wykes1 ; michelle.wykes@qimrberghofer.edu.au" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：16 August 2016
- 年：2016
- 卷：45
- 期：2
- 页码：333-345
- 全文大小：3733 K
文摘
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PD-L2 is essential for effective CD4+ T cell immunity
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PD-L2 determines the severity of malarial infections
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PD-L2 regulates the PD-1:PD-L1 axis
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Soluble PD-L2 can be an efficacious treatment for infectious diseases