CT detected indeterminate pulmonary nodules in a chemoprevention trial of fluticasone
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- 作者：Remco M. van den Berg ; H. Jelle Teertstra ; Nico van Z ; wijk ; Harm van Tinteren ; Christien Visser ; Arifa Pasic ; Thomas G. Sutedja ; Paul Baas ; Richard P. Golding ; Pieter E. Postmus ; Egbert F. Smit
- 关键词：Chemoprevention ; Computer tomography ; Inhaled corticosteroids ; Lung cancer ; Pulmonary nodules ; Trial
- 刊名：Lung Cancer
- 出版年：2008
- 出版时间：April 2008
- 年：2008
- 卷：60
- 期：1
- 页码：57-61
- 全文大小：223 K
文摘
In animal models of lung carcinogenesis, inhaled corticosteroids appear to reduce the number of new lung tumors. In a trial of budesonide in smokers with bronchial dysplasia, the proportion of indeterminate CT detected pulmonary nodules that resolved was larger in the treatment group. We performed a secondary analysis of CT data of subjects at risk of lung cancer enrolled in a chemoprevention trial of fluticasone.