Effects of road transportation on lymphocyte subsets in calves

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• 作者：Fulvio Riondato ; Antonio D’ ; Angelo ; Barbara Miniscalco ; Claudio Bellino ; Roberta Guglielmino
• 关键词：Cattle ; Stress ; Transport ; Flow cytometry ; Lymphocyte subsets
• 刊名：The Veterinary Journal
• 出版年：2008
• 出版时间：March 2008
• 年：2008
• 卷：175
• 期：3
• 页码：364-368
• 全文大小：166 K

文摘

The effect of transportation on peripheral blood lymphocyte subsets in 24 calves was investigated by flow cytometry. Blood was collected before departure, on arrival, at 24 h and 1 week after arrival. Highest leucocyte and neutrophil counts, associated with increased concentrations of cortisol and catecholamines, indicated that stress was maximal upon arrival. At this time, a decrease in the percentages of all T lymphocyte subsets was evident, while they did not decrease as absolute counts. The proportion of CD21⁺ cells did not change, indicating that the relative reduction of T lymphocyte subsets was not related to an increase in B lymphocytes. These variations may be due to the increase of a natural killer (NK) cell subset. NK cell expansion, together with increasing lymphocyte count and increasing major histocompatibility complex class II expression, may indicate stress-induced stimulation of the immune system.