Risperidone ameliorated Aβ_1-42-induced cognitive and hippocampal synaptic impairments in mice

详细信息    查看全文

• 作者：Lingzhi Wu ; Xiaowen Feng ; Tingting Li ; Baojuan Sun ; Muhammad Zahid Khan ; Ling He ; ^{heling92@hotmail.com} ; ^{hexyz@163.com}
• 关键词：Alzheimer&rsquo ; s disease ; Risperidone ; Cognitive impairment ; Aβ1-42
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：30 March 2017
• 年：2017
• 卷：322
• 期：part_PA
• 页码：145-156
• 全文大小：4111 K
• 卷排序：322

文摘

Risperidone improved the cognitive impairment of AD mice. Risperidone inhibited the generation of Aβ and p-Tau. Risperidone inhibited the neurons apoptosis induced by Aβ1-42.