Effects of methylphenidate on responses to novelty in a teleost fish (Poecilia reticulata)
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- 作者：Alex R. De Serrano ; 1 ; a.deserrano@utoronto.ca" class="auth_mail" title="E-mail the corresponding author ; Charmaine Fong1 ; F. Helen Rodd
- 关键词：Dopamine ; Exploratory behavior ; Guppy ; Ritalin® ; Novel object ; Open-field test
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：302
- 期：Complete
- 页码：53-59
- 全文大小：978 K
文摘
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Female guppies were treated with methylphenidate hydrochloride (Ritalin®).
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Fish were exposed to different novel stimuli: environment, object, or male.
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Treated fish were more exploratory in the novel environment and novel object test.
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Treated females were more responsive to the second male than controls.
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This suggests dopamine could alter novelty-seeking in this non-traditional model.