An ester-functionalized cationic gemini surfactant mediated structural transitions of porcine serum albumin (PSA) via binding interaction

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• 作者：Mohd. Akram^a ; ^{drmohdakram@rediffmail.com} ; Farah Ansari^a ; Imtiyaz Ahmad Bhat^a ; Sumit Kumar Chaturvedi^b ; Rizwan Hasan Khan^b ; Kabir-ud-Din^a ; ¹
• 关键词：Porcine serum albumin (PSA) ; 16-E2-16 ; Structural transitions
• 刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：516
• 期：Complete
• 页码：245-253
• 全文大小：2189 K
• 卷排序：516

文摘

Interaction of biodegradable ester-functionalized gemini surfactant 16-E2-16 with PSA. Spectroscopic and voltammetric techniques utilized for deciphering the binding phenomenon. Substantial binding with stabilization of secondary structure and negligible effect on tertiary structure of PSA. Potential applications in drug, skincare and immunoassay reagent formulations.