Bidirectional Anticipation of Future Osmotic Challenges by Vasopressin Neurons

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• 作者：Yael Mandelblat-Cerf¹ ; Angela Kim¹ ; ² ; Christian R. Burgess¹ ; Siva Subramanian¹ ; Bakhos A. Tannous² ; ³ ; Bradford B. Lowell¹ ; ² ; ^{blowell@bidmc.harvard.edu} ; Mark L. Andermann¹ ; ² ; ⁴ ; ^{manderma@bidmc.harvard.edu}
• 关键词：Vasopressin ; Fiber Photometry ; Electrophysiology ; Supraoptic nucleus ; Neuroendocrine neuron ; Posterior pituitary ; Presystemic ; Preingestive ; Food restriction ; Food and water cues ; Plasma osmolality
• 刊名：Neuron
• 出版年：2017
• 出版时间：4 January 2017
• 年：2017
• 卷：93
• 期：1
• 页码：57-65
• 全文大小：1659 K
• 卷排序：93

文摘

Recordings from vasopressin neuroendocrine motor neurons (VPpp) in behaving mice Feeding, but not cues predicting food, increase VPpp neuron activity within seconds Drinking and cues predicting water reduce VPpp neuron activity within seconds Drinking-related reductions in activity reach steady state prior to systemic feedback