Improved Prediction of CD34+ Cell Yield before Peripheral Blood Hematopoietic Progenitor Cell Collection Using a Modified Target Value-Tailored Approach
详细信息 查看全文
- 作者：Dawn Sheppard1 ; dsheppard@toh.on.ca" class="auth_mail" title="E-mail the corresponding author ; Jason Tay1 ; Douglas Palmer2 ; Anargyros Xenocostas3 ; Christina Doulaverakis3 ; Lothar Huebsch1 ; Sheryl McDiarmid1 ; Alan Tinmouth1 ; Ranjeeta Mallick1 ; Lisa Martin2 ; Paul Birch2 ; Linda Hamelin1 ; David Allan1 ; Christopher Bredeson1
- 关键词：Peripheral blood collection ; Apheresis ; Hematopoietic progenitor cells
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：763-767
- 全文大小：280 K
文摘
- •
There is no standard way to predict CD34+ cell yield during apheresis collection
- •
We have adapted a model to determine the blood volume to process
- •
The model was highly predictive of the number of CD34+ cells × 106/kg collected
- •
The model remained predictive when applied to an external data set