Role of LRV1 and RNAi in the Pathogenesis of Leishmania

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• 作者：Jean L. Patterson¹ ; ^{jpatters@TxBiomed.org}
• 关键词：LRV1 ; RNAi
• 刊名：Trends in Parasitology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：33
• 期：2
• 页码：76-78
• 全文大小：446 K
• 卷排序：33

文摘

The recent paper by Brettmann et al. provides insight as to how an RNA virus can persistently coexist in a protozoan with RNAi activity and how these two entities work to maintain balance. The authors were also able to successfully remove the virus and examine the role of the virus in parasitemia and the pathogenesis of leishmaniasis.