Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet
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- 作者：Rea P. Anunciado-Koza ; David C. Higgins ; Robert A. Koza ; rkoza@mmc.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mest ; Sfrp5 ; Bmp3 ; Obesity ; Epigenetics ; Genetics
- 刊名：Biochimie
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：124
- 期：Complete
- 页码：134-140
- 全文大小：1009 K
文摘
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Adipose Mest, Sfrp5 and Bmp3 are concomitant with strain-differences in adiposity.
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Correlation between Mest and Sfrp5 suggests a common regulatory mechanism.
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DBA/2J mice express high adipose tissue Sfrp5 compared to other mouse strains.
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DBA/2J, unlike B6 mice, shows no fat-inducible adipose Sfrp5 expression.
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Characteristics of DBA/2J provides excellent model to study Sfrp5 function.