Evaluation of the speed of kill, effects on reproduction, and effectiveness in a simulated infested-home environment of sarolaner (Simparicaℿ against fleas on dogs
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- 作者：Robert H. Sixa ; robert.six@Zoetis.com" class="auth_mail" title="E-mail the corresponding author ; Csilla Becskeib ; Lori Carterc ; Boyd Galed ; David R. Younge ; Sean P. Mahabira ; Sara Chapina ; Melanie R. Myersa
- 关键词：Ctenocephalides felis felis ; Dog ; Efficacy ; Environmental ; Flea ; Isoxazoline ; Oral ; Sarolaner ; Simparica&trade ; Speed of kill ; Reproduction
- 刊名：Veterinary Parasitology
- 出版年：2016
- 出版时间：30 May 2016
- 年：2016
- 卷：222
- 期：Complete
- 页码：23-27
- 全文大小：326 K
文摘
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Sarolaner started killing fleas within 3–4 h and lasted for more than a month.
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Sarolaner provided ≥98% control of fleas by 8 h for 28 days.
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A single treatment completely stopped flea egg laying for 35 days.
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In an infested environment model, >95% control of fleas was attained by 2 weeks and 100% efficacy was achieved after two monthly doses.