Rapid Recurrence of a Benign Meningial Perineurioma

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• 作者：Lukas Andereggen¹ ; ³ ; ⁴ ; Istvan Vajtai² ; Hans R. Widmer¹ ; Andreas Raabe¹ ; Robert H. Andres¹ ; ^{robert.andres@hin.ch" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Meningeal-based tumor ; Perineurioma ; Recurrence
• 刊名：World Neurosurgery
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：84
• 期：6
• 页码：2074.e1-2074.e3
• 全文大小：1058 K

文摘

We describe a rare case of a rapidly recurring benign meningial-based perineurioma. Clinical, radiologic, and pathologic features of a rapidly recurring falxial perineurioma are described; the perineurioma was discovered incidentally in an 86-year-old woman.

Case Description

Due to progressive gait disturbances and radiologically proven progression after a 3-year symptom-free interval, subtotal resection of a large falxial-based meningeal tumor was performed.

Conclusions

The pathologic examination confirmed the diagnosis of a perineurioma (World Health Organization grade I). Follow-up magnetic resonance tomography 5 months later due to neurologic deterioration revealed an abnormally rapidly growing and extensive local tumor recurrence. Due to the mass effect, reoperation was performed and adjuvant radiation of 20 Gy to the tumor bed was implemented thereafter. Meningeal-based perineuriomas of the central nervous system are extremely rare, and literature on proper management is scarce. Although histologic classification reveals a benign lesion, follow-up may be considered for this type of tumor.