Uncatalyzed, anti-Michael addition of amines to β-nitroacrylates: practical, eco-friendly synthesis of β-nitro-α-amino esters
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- 作者：Roberto Ballini ; Noelia Araú ; jo Bazá ; n ; Giovanna Bosica ; Aless ; ro Palmieri
- 关键词：Solvent free ; Anti-Michael addition ; Uncatalyzed reaction ; Amines ; β ; -Nitro-
; //www.sciencedirect.com/scidirimg/entities/204e.gif"" alt=""greek small letter alpha"" title=""greek small letter alpha"" border=""0"">-amino esters
- 刊名：Tetrahedron Letters
- 出版年：2008
- 出版时间：9 June 2008
- 年：2008
- 卷：49
- 期：24
- 页码：3865-3867
- 全文大小：95 K
文摘
A variety of primary and secondary amines give the conjugate reaction with β-nitroacrylates, via an anti-Michael addition, without any catalyst and/or solvent, allowing good yields of β-nitro-![]()
-amino esters.