¦Â-Nitroacrylates as key starting materials for the one-pot synthesis of densely functionalized penta-substituted anilines
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- 作者：Serena Gabrielli ; Aless ; ro Palmieri ; Deepak S. Panm ; Daniela Lanari ; Luigi Vaccaro ; Roberto Ballini
- 关键词：Anilines ; ¦Â-Nitroacrylates ; One-pot synthesis ; Ylidene malononitriles ; Conjugate addition
- 刊名：Tetrahedron
- 出版年：2012
- 出版时间：30 September, 2012
- 年：2012
- 卷：68
- 期：39
- 页码：8231-8235
- 全文大小：850 K
文摘
The reaction of ylidene malononitriles with ¦Â-nitroacrylates, in Et3N/MeCN, affords the one-pot synthesis of a new class of penta-substituted, densely functionalized anilines in satisfactory to good overall yields. The method represents a very important improvement of the recent strategy for the preparation of anilines from conjugated nitroalkenes.