Non-human primate antibody response to mosquito salivary proteins: Implications for dengue virus transmission in Puerto Rico
详细信息 查看全文
- 作者：Ryan R. Hemmea ; rhemme@cdc.gov" class="auth_mail" title="E-mail the corresponding author ; B. Katherine Poole-Smitha ; betty.k.poolesmith.mil@mail.mil" class="auth_mail" title="E-mail the corresponding author ; Elizabeth A. Hunspergera ; enh4@cdc.gov" class="auth_mail" title="E-mail the corresponding author ; Gilberto E. Felixa ; ckn5@cdc.gov" class="auth_mail" title="E-mail the corresponding author ; Kalanthe Horiuchib ; jqe2@cdc.gov" class="auth_mail" title="E-mail the corresponding author ; Brad J. Biggerstaffb ; bkb5@cdc.gov" class="auth_mail" title="E-mail the corresponding author ; Ricardo Lopez-Ortizc ; rlopez@drna.gobierno.pr" class="auth_mail" title="E-mail the corresponding author ; Roberto Barreraa ; amz9@cdc.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anti-salivary gland protein antibodies ; Dengue ; Non-human primates ; Aedes mediovittatus ; Aedes aegypti ; Culex quinquefasciatus
- 刊名：Acta Tropica
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：164
- 期：Complete
- 页码：369-374
- 全文大小：1249 K
文摘
- •
Twenty-two dengue virus infected non-human primates were evaluated for exposure to mosquito bites.
- •
Specific monkey antibody response to Aedes aegypti, Aedes mediovittatus, Aedes taeniorhynchus, and Culex quinquefasciatus salivary gland extract was evaluated.
- •
More non-human primates were positive for exposure to Aedes mediovittatus than any other mosquito species.
- •
Non-human primates and mosquitoes may be able to sustain dengue virus transmission during inter-epidemic periods.
- •
Mammalian antibody response to mosquito salivary glands has potential to incriminate cryptic or secondary vectors of disease causing pathogens.