Capsaicin 8% Patch in Painful Diabetic Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Study
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- 作者：David M. Simpson&lowast ; ; david.simpson@mssm.edu ; Jessica Robinson-Papp&lowast ; ; Joanna Van&dagger ; ; Malcolm Stoker&Dagger ; ; Hé ; lè ; ne Jacobs&Dagger ; ; Robert J. Snijder&Dagger ; ; Diederik S. Schregardus&Dagger ; ; § ; ; Stephen K. Long&Dagger ; ; ¶ ; ; Bruno Lambourg‖ ; Nathaniel Katz&lowast ; &lowast ; ; &dagger ; &dagger ;
- 关键词：Capsaicin 8% patch ; painful diabetic peripheral neuropathy ; NPRS average daily pain score ; Brief Pain Inventory-Diabetic Neuropathy ; phase 3 study
- 刊名：The Journal of Pain
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：18
- 期：1
- 页码：42-53
- 全文大小：1303 K
- 卷排序：18
文摘
Capsaicin 8% patch provided effective relief in painful diabetic peripheral neuropathy. Improvements in sleep quality were modest and significant with capsaicin 8% patch. Capsaicin 8% patch was well tolerated with no deterioration in sensory perception. Safety and tolerability were in line with previous studies of capsaicin 8% patch.