STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury
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- 作者：Amber R. Hackett1 ; Do-Hun Lee1 ; Abdul Dawood ; Mario Rodriguez ; Lucy Funk ; Pantelis Tsoulfas ; Jae K. Lee ; JLee22@med.miami.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：CNTF ; Ciliary neurotrophic factor ; CSPG ; Chondroitin sulfate proteoglycan ; DAPI ; 4&prime ; 6-Diamidino-2-phenylindole ; EdU ; 5-Ethynyl-2&prime ; -deoxyuridine ; GFAP ; Glial fibrillary acidic protein ; JAK ; Janus kinase ; LIF ; Leukemia inhibitory factor ; NG2 ; Neural glial antigen 2 ; OPC ; Oligodendrocyte progenitor cell ; SCI ; Spinal cord injury ; SOCS3 ; Suppressor of cytokine signaling 3 ; STAT3 ; Signal transducer and activator of transcription 3 ; TUNEL ; Terminal deoxynucleotidyl transferase (TdT) dUTP nic
- 刊名：Neurobiology of Disease
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：89
- 期：Complete
- 页码：10-22
- 全文大小：5256 K
文摘
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NG2 cell proliferation is regulated by SOCS3 after spinal cord injury (SCI)
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Oligodendrogenesis from NG2 cells is regulated by STAT3 after SCI
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STAT3/SOCS3 deletion does not affect astrogliogenesis from NG2 cells after SCI