Distribution of the outer membrane haem receptor protein ChuA in environmental and human isolates of Escherichia coli

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• 作者：Harald Hoffmann ; Mathias W. Hornef ; Sö ; ren Schubert ; Andreas Roggenkamp
• 关键词：Escherichia coli ; haem receptor ; ChuA
• 刊名：International Journal of Medical Microbiology
• 出版年：2001
• 出版时间：2001
• 年：2001
• 卷：291
• 期：3
• 页码：227-230
• 全文大小：63 K

文摘

ChuA, the haem receptor of Escherichia coli, is thought to contribute to the pathogenicity of E. coli strains causing extraintestinal infections. We investigated the prevalence and distribution of chuAin E. coli analysing 304 strains from different origins. 30 % of E. colistrains isolated from the environment and about 70 % of E. colistrains isolated from human sources carried chuA. No difference in chuA prevalence was found between commensals isolated from the intestine of healthy volunteers and isolates from extraintestinal infections. Our results indicate that ChuA might be involved in the colonization of human hosts.