Data are from 312 individuals (97 men and 215 women) aged 50 years and older. Body composition (dual energy X-ray absorptiometry) and knee extension strength of the right leg (1 repetition maximum) were assessed. Appendicular lean body mass index (AppLBMI) and MQ (knee extension strength /right leg lean mass) were calculated. A composite score of physical function was created based on the timed up-and-go, alternate step, sit-to-stand, and balance tests.
MQ was significantly associated with physical function when AppLBMI (尾聽= 0.179; P聽= .004) and body mass index (BMI) (尾聽= 0.178; P聽= .003), but not age (尾聽= 0.065; P聽= .26), were included in regression analysis. AppLBMI (尾聽= 0.221; P < .001), BMI (尾聽= 0.234; P < .001), and age (尾聽= 0.134; P聽= .018) significantly interacted with MQ to determine physical function.
Our results show that muscle mass, obesity, and age influence the relationship between MQ and physical function, suggesting that these factors should be taken into account when interpreting MQ. Even so, higher levels of MQ were associated with higher physical function scores. Nutritional and physical activity interventions may be designed in this regard.