Dietary arachidonic acid differentially regulates the gonadal steroidogenesis in the marine teleost, tongue sole (Cynoglossus semilaevis), depending on fish gender and maturation stage
Dietary ARA enhanced the testosterone production in mature tongue sole testis but reduced the estradiol production in ovary. Dietary ARA regulated gene expressions of sex steroid-synthesizing proteins depending on fish gender and maturation stage. ARA is preferentially accumulated in gonads, and testes showed higher ARA contents than ovaries. This is the first study observing the effects of fish gender and maturation stage on regulation of steroidogenesis by ARA.