Taurine promotes cognitive function in prenatally stressed juvenile rats via activating the Akt-CREB-PGC1α pathway
详细信息 查看全文
- 作者：Ning Jiaa ; jianing@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qinru Sunb ; qinrusun@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qian Suc ; Shaokang Dangc ; Guomin Chena
- 关键词：Prenatal stress ; Hippocampus ; Mitochondria ; Taurine ; Akt-CREB-PGC1α pathway
- 刊名：Redox Biology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：10
- 期：Complete
- 页码：179-190
- 全文大小：1997 K
文摘
- •
Taurine attenuates prenatal stress (PS)-induced cognitive impairment.
- •
Taurine reduces PS-induced neuronal apoptosis and mitochondrial dysfunction.
- •
Taurine maintains the activities of SOD2 and catalase to repress ROS.
- •
Taurine activates PS-suppressed Akt-CREB-PGC1α pathway.