Somatosensory-evoked potential modulation by quadripulse transcranial magnetic stimulation in patients with benign myoclonus epilepsy
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- 作者：Setsu Nakatani-Enomotoa ; b ; setsu-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Ritstuko Hanajimab ; d ; hanajima-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Masashi Hamadab ; mhamada-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yasuo Teraob ; saccade@hotmail.co.jp" class="auth_mail" title="E-mail the corresponding author ; Hideyuki Matsumotob ; hideyukimatsumoto.jp@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yuichiro Shirotab ; h ; you_shirota@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author ; Shinya Ohminamib ; oominami-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shingo Okabeb ; okabes@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Masaki Hirosea ; masakihirose1977@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author ; Koichiro Nakamuraa ; knaka0325@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author ; Toshiaki Furubayashia ; b ; c ; furu@rehab.tbgu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Stefan Jun Groissa ; e ; StefanJun.Groiss@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author ; Shunsuke Kobayashia ; skoba-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hitoshi Mochizukia ; g ; mochizuki-h@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hiroyuki Enomotoa ; enomoto-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yoshikazu Ugawaa ; b ; f ; ugawa-tky@umin.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：Quadripulse transcranial magnetic stimulation (QPS) ; Benign myoclonus epilepsy ; Somatosensory-evoked potential (SEP) ; Long-term potentiation (LTP) ; Long-term depression (LTD)
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：127
- 期：2
- 页码：1560-1567
- 全文大小：791 K
文摘
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In healthy subjects, quadripulse transcranial magnetic stimulation (QPS) over the primary motor cortex (M1) induces bidirectional heterotopic plasticity in the somatosensory cortex (S1), following the Bienenstock–Cooper–Munro (BCM)-like theory.
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In patients with benign myoclonus epilepsy (ME patients), QPS over M1 induces long-term potentiation (LTP) but no long-term depression (LTD) in S1.
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QPS is not applicable to the treatment for ME patients because the frequency dependency may be completely different between the healthy subjects and the patients.