The synthesis of (4S

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• 作者：Maria D. Rozwadowska ; Anna Tomczak
• 刊名：Tetrahedron: Asymmetry
• 出版年：2009
• 出版时间：8 September 2009
• 年：2009
• 卷：20
• 期：17
• 页码：2048-2051
• 全文大小：267 K

文摘

(4S,5S)-(−)-Isocytoxazone, which is needed for a configurational study, was synthesized from the commercially available (1S,2S)-(+)-2-amino-1-(4-nitrophenyl)-1,3-propanediol in which the p-nitro substituent was replaced by a p-methoxyl group; the thus prepared p-methoxyphenyl amino diol was cyclized via an N-Boc derivative.