d="par0005">Various risk factors may interact to precipitate presymptomatic Parkinson’s disease.
dd><dt class="label">•dt><dd>d="par0010">We investigated the interaction between α-synuclein and the pesticide, rotenone.
dd><dt class="label">•dt><dd>d="par0015">Dual exposure to α-synuclein and rotenone precipitated Parkinsonism in rats.
dd><dt class="label">•dt><dd>d="par0020">Rats exposed to both factors had profound motor dysfunction and neurodegeneration.
dd><dt class="label">•dt><dd>d="par0025">This highlights the importance of these interactions in Parkinson’s disease.
dd>dl>