Preparation of magnetic ODS-PAN thin-films for microextraction of quetiapine and clozapine in plasma and urine samples followed by HPLC-UV detection
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- 作者：Dan Li ; Juan Zou ; Pei-Shan Cai ; Chao-Mei Xiong ; cmxiong2002@hust.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jin-Lan Ruan
- 关键词：Magnetic octadecylsilane-polyacrylonitrile thin-film microextraction (ODS-PAN TFME) ; HPLC-UV ; Quetiapine ; Clozapine ; Therapeutic drug monitoring (TDM) ; Plasma ; Urine
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：5 June 2016
- 年：2016
- 卷：125
- 期：Complete
- 页码：319-328
- 全文大小：2220 K
文摘
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Conventional TFME was first endowed with magnetic by introducing SiO2@Fe3O4.
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The magnetic property of thin-films creates a more handy operation way of TFME.
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The magnetic TFME was successfully applied for clinical plasma and urine samples.