Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation
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- 作者：Zhongyu Xie1 ; 13 ; Di Zhang1 ; 13 ; Dongjun Chung2 ; 3 ; 13 ; Zhanyun Tang4 ; He Huang1 ; Lunzhi Dai1 ; Shankang Qi1 ; Jingya Li5 ; Gozde Colak1 ; Yue Chen1 ; Chunmei Xia5 ; Chao Peng1 ; Haibin Ruan6 ; Matt Kirkey7 ; Danli Wang1 ; Lindy M. Jensen8 ; Oh Kwang Kwon9 ; Sangkyu Lee9 ; Scott D. Pletcher8 ; Minjia Tan5 ; David B. Lombard10 ; Kevin P. White7 ; Hongyu Zhao2 ; 11 ; 12 ; Jia Li5 ; Robert G. Roeder4 ; Xiaoyong Yang6 ; xiaoyong.yang@yale.edu" class="auth_mail" title="E-mail the corresponding author ; Yingming Zhao1 ; yingming.zhao@uchicago.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：21 April 2016
- 年：2016
- 卷：62
- 期：2
- 页码：194-206
- 全文大小：2396 K
文摘
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Lysine β-hydroxybutyrylation (Kbhb) is a new type of histone mark
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44 non-redundant histone Kbhb sites are identified in human and mouse cells
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Histone Kbhb increases under starvation and STZ-induced ketoacidosis
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Starvation-induced H3K9bhb is associated with active gene expression