Tobacco and e-cigarette products initiate Kupffer cell inflammatory responses
详细信息 查看全文
- 作者：David A. Rubensteina ; david.rubenstein@stonybrook.edu" class="auth_mail" title="E-mail the corresponding author ; Sarah Homa ; Berhane Ghebrehiwetb ; Wei Yina
- 关键词：gC1qR ; receptor for the globular head of C1q ; cC1qR ; receptor for the collagen region of C1q
- 刊名：Molecular Immunology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：67
- 期：2
- 页码：652-660
- 全文大小：1414 K
文摘
- •
Kupffer cells are responsive to classical cardiovascular risk factors.
- •
Kupffer cells can support complement activation and express gC1qR and cC1qR.
- •
After exposure to cigarettes, Kupffer cell activate innate immune responses.
- •
Liver innate immune responses may activate other cardiovascular cells.