LC-MS/MS determination and urinary excretion study of seven alkaloids in healthy Chinese volunteers after oral administration of Shuanghua Baihe tablets
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- 作者：Minlu Chenga ; b ; 1 ; Ruijuan Liua ; b ; 1 ; Yao Wua ; b ; Pan Gua ; b ; Lu Zhengc ; Yujie Liuc ; Pengcheng Mad ; mpc815@163.com" class="auth_mail" title="E-mail the corresponding author ; Li Dinga ; b ; dinglidl@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：SBT ; Shuanghua Baihe tablets ; IS ; internal standard ; LLOQ ; lower limit of quantification ; LQC ; low QC ; MQC ; medium QC ; HQC ; high QC ; MRM ; multiple reaction monitoring ; RE ; relative error
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：25 January 2016
- 年：2016
- 卷：118
- 期：Complete
- 页码：89-95
- 全文大小：1674 K
文摘
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An LC–MS/MS method for the simultaneous determination of seven alkaloids in human urine.
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The first urinary excretion study of Shuanghua Baihe tablets in healthy Chinese volunteers.
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The first excretion profiles of the seven alkaloids except berberine in human urine.