Controlling angiogenesis in gastric cancer: A systematic review of anti-angiogenic trials
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- 作者：Fei Shan ; Rulin Miao ; Kan Xue ; Zhemin Li ; Ziyu Li ; Zhaode Bu ; Aiwen Wu ; Lianhai Zhang ; Xiaojiang Wu ; Xianglong Zong ; Xiaohong Wang ; Shuangxi Li ; Xin Ji ; Ziyu Jia ; Ziran Li ; Jiafu Ji ; jiafuj@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gastric neoplasms ; Angiogenesis inhibitors ; Antineoplastic agents ; Vascular endothelial growth factor antagonists and inhibitors ; Controlled clinical trial ; Antineoplastic combined chemotherapy protocols
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：380
- 期：2
- 页码：598-607
- 全文大小：322 K
文摘
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Most anti-angiogenic agents are reported to improve in response rate, but not progression-free survival or overall survival compared to chemotherapy alone.
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Only ramucirumab has been demonstrated to improve outcome as secondary-line treatment in advance gastric cancer.
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Searching robust biological predictors (biomarkers) to stratify patients.