The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: A new approach to risk assessment and disease prevention
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- 作者：Antonio Ivan Lazzarino ; MD PhDa ; b ; antonio.lazzarino@lshtm.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Mark Hamer ; PhDe ; David Gaze ; PhDc ; Paul Collinson ; MDc ; Ann Rumley ; PhDd ; Gordon Lowe ; DScd ; Andrew Steptoe ; DScb
- 关键词：Allostasis ; Atherosclerosis ; Cardiovascular diseases ; Fibrinogen ; Neuroendocrinology ; Psychological stress ; Socioeconomic factors ; Troponin T
- 刊名：Preventive Medicine
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：93
- 期：Complete
- 页码：46-52
- 全文大小：244 K
文摘
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Chronic psychosocial stress modifies the association between inflammation and CVD.
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A single test result of elevated fibrinogen can be the result of a healthy acute response to stress.
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Therefore a finding of elevated fibrinogen cannot always be interpreted as a sign of poor health.
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Elevated fibrinogen is associated with CVD only in individuals with chronic stress.