Abnormal ephrinBs and EphBs mRNA expression were observed in patients and rats with intractable temporal lobe epilepsy (TLE).
ephrinB3 and EphB3 were up-regulated in intractable TLE patients and rats.
ephrinB3 located in both glia and neurons, EphB3 located in neurons.
ephrinB3 and EphB3 may serve as potential biomarkers for predicting TLE.