High-dose circumferential chemodenervation of the internal anal sphincter: A new treatment modality for uncomplicated chronic anal fissure: A retrospective cohort study (with video)
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- 作者：Porter H. Glovera ; Shou-jiang Tanga ; stang@umc.edu" class="auth_mail" title="E-mail the corresponding author ; James Z. Whatleya ; Eric D. Davisa ; Kellen T. Jexa ; Ruonan Wua ; Christopher J. Lahrb
- 关键词：High-dose circumferential chemodenervation ; Chronic anal fissure ; Injection ; Botulinum toxin ; Lateral internal sphincterotomy ; Healing rate
- 刊名：International Journal of Surgery
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：23
- 期：part_PA
- 页码：1-4
- 全文大小：465 K
文摘
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Botulinum toxin injection into the anal sphincter is effective for anal fissures.
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High-dose circumferential chemodenervation (HDCC) with 100 IU botulinum toxin.
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HDCC achieved a healing rate of 90.7% at 3 months.
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At 2 weeks and 3 months, there were no major adverse outcomes.