“One pot” synthesis of tertiary amines: Ru(II) catalyzed direct reductive N-benzylation of imines with benzyl bromide derivatives

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• 作者：Bin Li^a ; ^{andonlee@163.com} ; Jinghao Yu^a ; ^b ; Caihua Li^a ; Yibiao Li^a ; ^{leeyib268@126.com} ; Jianli Luo^b ; Yan Shao^a
• 关键词：Reductive N-benzylation ; Ruthenium catalysis ; Hydrosilylane ; Tertiary amines
• 刊名：Tetrahedron Letters
• 出版年：2017
• 出版时间：11 January 2017
• 年：2017
• 卷：58
• 期：2
• 页码：137-141
• 全文大小：908 K
• 卷排序：58

文摘

Tertiary amines were synthesized via reductive N-benzylation by using [RuCl2(p-cymene)]2 catalyst. Interesting functional group tolerance and good chemoselectivities were shown. A mechanism of the reductive N-benzylation was proposed.