The link between autonomic responsivity towards socioaffective stimuli and anxiety was investigated among those with Williams syndrome (WS).
Those with WS yielded higher anxiety ratings than typically developing (TD) individuals.
Individuals with WS showed a specific difficulty in recognising anger across the social stimuli.
No significant group differences were observed in autonomic reactivity to social-affective stimuli.
Less autonomic arousal to angry social stimuli was related to higher anxiety in WS uniquely.