Ryanodine receptor point mutations confer diamide insecticide resistance in tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae)

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• 作者：Emmanouil Roditakis^a ; ^{eroditakis@nagref.gr} ; Denise Steinbach^b ; ^c ; Gerald Moritz^c ; Emmanouil Vasakis^a ; Marianna Stavrakaki^a ; Aris Ilias^a ; Lidia Garcí ; a-Vidal^d ; Marí ; a del Rosario Martí ; nez-Aguirre^d ; Pablo Bielza^d ; Evangelia Morou^e ; Jefferson E. Silva^f ; Wellington M. Silva^f ; Ηerbert A.A. Siqueira^f ; Sofia Iqbal^g ; Bartlomiej J. Troczka^g ; Martin S. Williamson^g ; Chris Bass^h ; Anastasia Tsagkarakou^a ; John Vontas^e ; ⁱ ; Ralf Nauen^b ; ^{ralf.nauen@bayer.com}
• 关键词：Tuta absoluta ; Diamide resistance ; Flubendiamide ; Chlorantraniliprole ; Ryanodine receptor ; Target-site mutation
• 刊名：Insect Biochemistry and Molecular Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：80
• 期：Complete
• 页码：11-20
• 全文大小：1038 K
• 卷排序：80

文摘

Diamides are major weapon against Tuta absoluta; however, resistance evolved. Diamide resistance has an autosomal incompletely recessive mode of inheritance. Known and novel alternative RyR mutations were associated with the phenotype. Radioligand binding: these mutations alter the affinity of the RyR to diamides. Diamide resistance mutations are present in T. absoluta populations worldwide.