Vanillin mitigates potassium bromate-induced molecular, biochemical and histopathological changes in the kidney of adult mice
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- 作者：Hajer Ben Saada ; hajerbensaad21@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Dorra Drissb ; Samia Ellouz Chaabounib ; Tahia Boudawarac ; Khaled Mounir Zeghala ; Ahmed Hakima ; 1 ; Ibtissem Ben Amarad ; 1
- 关键词：Vanillin ; Potassium bromate ; Metallothionein ; Genes expression ; Antioxidant activity
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：25 May 2016
- 年：2016
- 卷：252
- 期：Complete
- 页码：102-113
- 全文大小：1690 K
文摘
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Vanillin, an antioxidant, prevents renal injury induced by KBrO3 in adult mice.
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Vanillin reduced malondialdehyde and raised non-enzymatic antioxidant activities.
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Vanillin reduced the activities and gene expression of glutathione peroxidase and glutathione.
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Vanillin improved the histological aspect in the kidney of adult mice.
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Vanillin decreased mRNA expression and the level of metallothionein in KBrO3 treated mice.