The tetranucleotide repeat polymorphism C2_4_4: population data and linkage disequilibria with HLA class I
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- 作者：Simone Stadlbacher ; Eva-Maria Dauber ; Sabine Wenda ; Barbara Glock ; Maria Hafner ; Gü ; nther F. Kö ; rmö ; czi ; Wolfgang R. Mayr
- 关键词：Langerhans cells
- 刊名：Immunobiology
- 出版年：2003
- 出版时间：2003
- 年：2003
- 卷：207
- 期：2
- 页码：137-140
- 全文大小：58 K
文摘
The tetranucleotide repeat locus C2_4_4 situated in the HLA class I region (6p21.3) and the HLA-ABC specificities were investigated in an Austrian population sample of 240 unrelated Caucasoid individuals. The analysis of the linkage disequilibrium between C2_4_4 and HLA class I showed several significant values, especially when factors coded for by so-called “superhaplotypes” were considered; such linkage disequilibria are of importance for the practical use of HLA coded short tandem repeats.