Graft-versus-Host Disease after HLA-Matched Sibling Bone Marrow or Peripheral Blood Stem Cell Transplantation: Comparison of North American Caucasian and Japanese Populations
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- 作者：Junya Kanda1 ; Ruta Brazauskas2 ; Zhen-Huan Hu3 ; Yachiyo Kuwatsuka4 ; Koji Nagafuji5 ; Heiwa Kanamori6 ; Yoshinobu Kanda1 ; Koichi Miyamura7 ; Makoto Murata8 ; Takahiro Fukuda9 ; Hisashi Sakamaki10 ; Fumihiko Kimura11 ; Sachiko Seo12 ; Mahmoud Aljurf13 ; Ayami Yoshimi14 ; Giuseppe Milone15 ; William A. Wood16 ; Celalettin Ustun17 ; Shahrukh Hashimi18 ; Marcelo Pasquini3 ; Carmem Bonfim19 ; Jignesh Dalal20 ; Theresa Hahn21 ; Yoshiko Atsuta22 ; 23 ; y-atsuta@jdchct.or.jp" class="auth_mail" title="E-mail the corresponding author ; Wael Saber3 ; wsaber@mcw.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Graft-versus-host disease ; Bone marrow transplantation ; Peripheral blood stem cell transplantation ; Race
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：744-751
- 全文大小：619 K
文摘
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The impact of race on transplantation outcomes was independent of graft source.
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The risk of severe acute GVHD was lower in the Japanese patients compared with the Caucasian patients.
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The lower risk of acute GVHD resulted in a lower risk of nonrelapse mortality in the Japanese patients.
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The risk of relapse was lower in the Japanese patients compared with the Caucasian patients.
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Overall survival was higher in the Japanese patients compared with the Caucasian patients.