Hydroxyapatite-hybridized chitosan/chitin whisker bionanocomposite fibers for bone tissue engineering applications
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- 作者：Autchara Pangon ; autchara@nanotec.or.th" class="auth_mail" title="E-mail the corresponding author ; p_autchara@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Somsak Saesoo ; Nattika Saengkrit ; Uracha Ruktanonchai ; Varol Intasanta
- 关键词：Chitosan ; Chitin whisker ; Bionanocomposite ; Hydroxyapatite ; Electrospun nanofiber ; Bone tissue engineering scaffold
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：25 June 2016
- 年：2016
- 卷：144
- 期：Complete
- 页码：419-427
- 全文大小：2350 K
文摘
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Hydroxyapatite-hybridized chitosan/chitin whisker bionanocomposite fibers for potential applications in bone tissue engineering were prepared.
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Mechanical properties of the chitosan/chitin whisker bionanocomposite fibers were improved by hydroxyapatite hybridization.
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Young’s modulus of the bionanocomposite and HA-hybridized nanofibers was enhanced by CTWK integration.
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Cell viability and proliferation of osteoblast cells on the HA-hybridized scaffolds were enhanced by incorporation of CTWK.