Novel intergenotype human norovirus recombinant GII.16/GII.3 in Bangladesh
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- 作者：Shamsun Nahar ; Mokibul Hassan Afrad ; Jelle Matthijnssens ; Mohammed Ziaur Rahman ; Zehadee Momtaz ; Rahena Yasmin ; Mohammad Jubair ; Abu Syed Golam Faruque ; Mohammad Sahabuddin Kabir Choudhuri ; Tasnim Azim ; Mustafizur Rahman
- 关键词：Norovirus ; Recombinant ; GII.16 ; GII.3 ; Diarrhea ; Bangladesh
- 刊名：Infection, Genetics and Evolution
- 出版年：December, 2013
- 年：2013
- 卷：20
- 期：Complete
- 页码：325-329
- 全文大小：351 K
文摘
Noroviruses (NoVs) are one of the major etiological agents of acute gastroenteritis in all age groups. In this study, we identified an intergenotype NoV recombinant strain in the fecal specimens of two male infants with acute diarrhea in Bangladesh. Phylogenetic analysis showed that the identified strains were recombinant NoV strains with a GII.3 capsid and a GII.16 polymerase gene. The recombination breakpoint was located in the ORF1/ORF2 overlap region. To the best of our knowledge this is the first report of a NoV recombinant GII.16/GII.3 strain worldwide.