Structural changes of nucleic acid base in aqueous solution as observed in X-ray absorption near edge structure (XANES)

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• 作者：Hiroyuki Shimada ; Taishi Fukao ; Hirotake Minami ; Masatoshi Ukai ; Kentaro Fujii ; Akinari Yokoya ; Yoshihiro Fukuda ; Yuji Saitoh
• 刊名：Chemical Physics Letters
• 出版年：20 January, 2014
• 年：2014
• 卷：591
• 期：Complete
• 页码：137-141
• 全文大小：513 K

文摘

X-ray absorption near edge structure (XANES) spectra for adenine-containing nucleotides, adenosine 5鈥?monophosphate (AMP) and adenosine 5鈥?triphosphate (ATP) in aqueous solutions at the nitrogen K-edge region were measured. The two intense peaks in XANES spectra are assigned to transitions of 1s electrons to the 蟺^{鈭?/sup> orbitals of different types of N atoms with particular bonding characteristics. The difference between their spectra is ascribed to protonation of a particular N atom. Similarity observed in XANES spectra of guanosine 5鈥?monophosphate (GMP) and ATP is also interpreted as similar bonding characters of the N atoms in the nucleobase moiety.}